Wednesday, November 3, 2010

Biology

Noise in Genetic Circuits: Eldar and Elowitz
If you spend some time modeling a particular developmental or regulatory system in biology you will realize that various architectures can result in identical functions in a deterministic limit. Considering noise however can bias particular wirings over others from an evolutionary standpoint. This paper elaborates upon three generic circuits 1) state switching 2) excitability and 3) procrastination. Each one depends on noise in a characteristic way and biases certain phenotypic responses over others.

No comments: